April 20, 2020
We focus on the problem of training convolutional neural networks on gigapixel histopathology images to predict image-level targets. For this purpose, we extend Neural Image Compression (NIC), an image compression framework that reduces the dimensionality of these images using an encoder network trained unsupervisedly. We propose to train this encoder using supervised multitask learning (MTL) instead. We applied the proposed MTL NIC to two histopathology datasets and three tasks. First, we obtained state-of-the-art results in the Tumor Proliferation Assessment Challenge of 2016 (TUPAC16). Second, we successfully classified histopathological growth patterns in images with colorectal liver metastasis (CLM). Third, we predicted patient risk of death by learning directly from overall survival in the same CLM data. Our experimental results suggest that the representations learned by the MTL objective are: (1) highly specific, due to the supervised training signal, and (2) transferable, since the same features perform well across different tasks. Additionally, we trained multiple encoders with different training objectives, e.g. unsupervised and variants of MTL, and observed a positive correlation between the number of tasks in MTL and the system performance on the TUPAC16 dataset.
Written by
Michal Drozdzal
Cornelis Verhoef
David Tellez
Diederik Hoppener
Dirk Grunhagen
Francesco Ciompi
Jeroen van der Laak
Pieter Nierop
Publisher
MIDL
Research Topics
February 07, 2025
Andros Tjandra, Yi-Chiao Wu, Baishan Guo, John Hoffman, Brian Ellis, Apoorv Vyas, Bowen Shi, Sanyuan Chen, Matt Le, Nick Zacharov, Carleigh Wood, Ann Lee, Wei-Ning Hsu
February 07, 2025
February 06, 2025
Jarod Levy, Mingfang (Lucy) Zhang, Svetlana Pinet, Jérémy Rapin, Hubert Jacob Banville, Stéphane d'Ascoli, Jean Remi King
February 06, 2025
February 06, 2025
Mingfang (Lucy) Zhang, Jarod Levy, Stéphane d'Ascoli, Jérémy Rapin, F.-Xavier Alario, Pierre Bourdillon, Svetlana Pinet, Jean Remi King
February 06, 2025
December 12, 2024
Melissa Hall, Oscar Mañas, Reyhane Askari, Mark Ibrahim, Candace Ross, Pietro Astolfi, Tariq Berrada Ifriqi, Marton Havasi, Yohann Benchetrit, Karen Ullrich, Carolina Braga, Abhishek Charnalia, Maeve Ryan, Mike Rabbat, Michal Drozdzal, Jakob Verbeek, Adriana Romero Soriano
December 12, 2024
Foundational models
Our approach
Latest news
Foundational models